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rabbit polyclonal antibody to notch3  (Danaher Inc)


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    Structured Review

    Danaher Inc rabbit polyclonal antibody to notch3
    <t>NOTCH3</t> expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer
    Rabbit Polyclonal Antibody To Notch3, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 99/100, based on 20243 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+notch3+antibody/Rabbit+Polyclonal+Anti-JAK2+(phospho+Y1007)+antibody/pmc09392971-43-22-28
    Average 99 stars, based on 20243 article reviews
    rabbit polyclonal antibody to notch3 - by Bioz Stars, 2026-09
    99/100 stars

    Images

    1) Product Images from "The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients"

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    Journal: Bosnian Journal of Basic Medical Sciences

    doi: 10.17305/bjbms.2021.6767

    NOTCH3 expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer
    Figure Legend Snippet: NOTCH3 expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer

    Techniques Used: Expressing, Staining


    Figure Legend Snippet: Histopathological and clinical characteristics of urothelial bladder cancer patients according to NOTCH3 expression

    Techniques Used: Expressing


    Figure Legend Snippet: Post hoc analysis with semi-quantified NOTCH3 expression

    Techniques Used: Expressing


    Figure Legend Snippet: Patients’ survival according to NOTCH3 expression

    Techniques Used: Expressing

    Kaplan–Meier survival curves showing overall survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=diffuse, intermediate staining; 3=strong, diffuse staining) NOTCH3 expression.
    Figure Legend Snippet: Kaplan–Meier survival curves showing overall survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=diffuse, intermediate staining; 3=strong, diffuse staining) NOTCH3 expression.

    Techniques Used: Staining, Expressing

    Kaplan–Meier survival curves showing cancer-specific survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2= intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.
    Figure Legend Snippet: Kaplan–Meier survival curves showing cancer-specific survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2= intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Techniques Used: Staining, Expressing

    Kaplan–Meier survival curves showing recurrence-free survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.
    Figure Legend Snippet: Kaplan–Meier survival curves showing recurrence-free survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Techniques Used: Staining, Expressing

    Related Articles

    Immunocytochemistry:

    Article Title: Transendocytosis is impaired in CADASIL-mutant NOTCH3.
    Article Snippet: Contents lists available at SciVerse ScienceDirect Experimental Neurology j ourna l homepage: www.e lsev ie r .com/ locate /yexnr Regular Article Transendocytosis is impaired in CADASIL-mutant NOTCH3 Akiko Watanabe-Hosomi a, Yoshihisa Watanabe b, Masaki Tanaka b, Masanori Nakagawa a, Toshiki Mizuno a,⁎ a Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan b Department of Basic Geriatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan ⁎ Corresponding author at: Department of Neurology of Medicine, Kajiicho-465, Kamigyo-ku, Kyoto 602-8566 E-mail address: mizuno@koto.kpu-m.ac.jp (T. Mizun 0014-4886/$ – see front matter © 2011 Elsevier Inc. All doi:10.1016/j.expneurol.2011.10.020 a b s t r a c t a r t i c l e i n f o

    Western Blot:

    Article Title: Transendocytosis is impaired in CADASIL-mutant NOTCH3.
    Article Snippet: Contents lists available at SciVerse ScienceDirect Experimental Neurology j ourna l homepage: www.e lsev ie r .com/ locate /yexnr Regular Article Transendocytosis is impaired in CADASIL-mutant NOTCH3 Akiko Watanabe-Hosomi a, Yoshihisa Watanabe b, Masaki Tanaka b, Masanori Nakagawa a, Toshiki Mizuno a,⁎ a Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan b Department of Basic Geriatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan ⁎ Corresponding author at: Department of Neurology of Medicine, Kajiicho-465, Kamigyo-ku, Kyoto 602-8566 E-mail address: mizuno@koto.kpu-m.ac.jp (T. Mizun 0014-4886/$ – see front matter © 2011 Elsevier Inc. All doi:10.1016/j.expneurol.2011.10.020 a b s t r a c t a r t i c l e i n f o

    other:

    Article Title: Regulation of gliomagenesis and stemness through acid sensor ASIC1a
    Article Snippet: Rabbit polyclonal anti-Notch3 antibody (product code ab60087) was purchased from Abcam.



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    <t>NOTCH3</t> expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer
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    Image Search Results


    NOTCH3 expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer

    Journal: Bosnian Journal of Basic Medical Sciences

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    doi: 10.17305/bjbms.2021.6767

    Figure Lengend Snippet: NOTCH3 expression in UBC; (A) NOTCH3-positive endothelial cells and NOTCH3-negative (0) tumor cells in pTa UBC (×100); (B) intermediate, focal NOTCH3 (1) staining in high-grade pT1 UBC (×200); (C) intermediate, diffuse NOTCH3 (2) staining in low-grade pT1 UBC (×100); (D) intense, diffuse NOTCH3 (3) staining in pT2 UBC (×200). UBC: Urothelial bladder cancer

    Article Snippet: After preparation, the slides were processed in a semi-automatic IHC diagnostic system (Ventana Inc.) and the IHC staining was performed using a rabbit polyclonal antibody to NOTCH3 (ab23426, Abcam, Cambridge, UK) at a concentration of 5 mg/ml.

    Techniques: Expressing, Staining

    Journal: Bosnian Journal of Basic Medical Sciences

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    doi: 10.17305/bjbms.2021.6767

    Figure Lengend Snippet: Histopathological and clinical characteristics of urothelial bladder cancer patients according to NOTCH3 expression

    Article Snippet: After preparation, the slides were processed in a semi-automatic IHC diagnostic system (Ventana Inc.) and the IHC staining was performed using a rabbit polyclonal antibody to NOTCH3 (ab23426, Abcam, Cambridge, UK) at a concentration of 5 mg/ml.

    Techniques: Expressing

    Kaplan–Meier survival curves showing overall survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=diffuse, intermediate staining; 3=strong, diffuse staining) NOTCH3 expression.

    Journal: Bosnian Journal of Basic Medical Sciences

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    doi: 10.17305/bjbms.2021.6767

    Figure Lengend Snippet: Kaplan–Meier survival curves showing overall survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=diffuse, intermediate staining; 3=strong, diffuse staining) NOTCH3 expression.

    Article Snippet: After preparation, the slides were processed in a semi-automatic IHC diagnostic system (Ventana Inc.) and the IHC staining was performed using a rabbit polyclonal antibody to NOTCH3 (ab23426, Abcam, Cambridge, UK) at a concentration of 5 mg/ml.

    Techniques: Staining, Expressing

    Kaplan–Meier survival curves showing cancer-specific survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2= intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Journal: Bosnian Journal of Basic Medical Sciences

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    doi: 10.17305/bjbms.2021.6767

    Figure Lengend Snippet: Kaplan–Meier survival curves showing cancer-specific survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2= intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Article Snippet: After preparation, the slides were processed in a semi-automatic IHC diagnostic system (Ventana Inc.) and the IHC staining was performed using a rabbit polyclonal antibody to NOTCH3 (ab23426, Abcam, Cambridge, UK) at a concentration of 5 mg/ml.

    Techniques: Staining, Expressing

    Kaplan–Meier survival curves showing recurrence-free survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Journal: Bosnian Journal of Basic Medical Sciences

    Article Title: The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

    doi: 10.17305/bjbms.2021.6767

    Figure Lengend Snippet: Kaplan–Meier survival curves showing recurrence-free survival of 614 bladder cancer patients with negative (0=no staining; 1=weak and/or focal staining) and positive (2=intermediate, diffuse staining; 3=strong, diffuse staining) NOTCH3 expression.

    Article Snippet: After preparation, the slides were processed in a semi-automatic IHC diagnostic system (Ventana Inc.) and the IHC staining was performed using a rabbit polyclonal antibody to NOTCH3 (ab23426, Abcam, Cambridge, UK) at a concentration of 5 mg/ml.

    Techniques: Staining, Expressing

    Notch signaling is negatively associated with ASIC1a in glioblastoma multiforme. (A-C) The glioma cells were transfected with shASIC1a and control followed by assaying protein expression of ASIC1a, active form of Notch1, Notch2, Notch3, Notch4, and Notch target survivin, as well as GSC markers CD133 and ALDH1 by western blotting in (A) A172, (B) U87MG, and (C) PDX-L12 cells. (D-F) Subsequently, the glioma cells (D) A172, (E) U87MG and (F) PDX-L12 were transfected with ASIC1a-FLAG followed by assaying protein expression of ASIC1a, active form of Notch1, Notch2, Notch3, Notch4 and Notch target survivin, as well as GSC markers CD133 and ALDH1 by western blotting. * P<0.05 and ** P<0.01. ASIC1a, acid-sensing ion channel 1a; sh, short hairpin; GSC, glioblastoma stem cells; ALDH1, aldehyde dehydrogenase 1.

    Journal: International Journal of Oncology

    Article Title: Regulation of gliomagenesis and stemness through acid sensor ASIC1a

    doi: 10.3892/ijo.2021.5262

    Figure Lengend Snippet: Notch signaling is negatively associated with ASIC1a in glioblastoma multiforme. (A-C) The glioma cells were transfected with shASIC1a and control followed by assaying protein expression of ASIC1a, active form of Notch1, Notch2, Notch3, Notch4, and Notch target survivin, as well as GSC markers CD133 and ALDH1 by western blotting in (A) A172, (B) U87MG, and (C) PDX-L12 cells. (D-F) Subsequently, the glioma cells (D) A172, (E) U87MG and (F) PDX-L12 were transfected with ASIC1a-FLAG followed by assaying protein expression of ASIC1a, active form of Notch1, Notch2, Notch3, Notch4 and Notch target survivin, as well as GSC markers CD133 and ALDH1 by western blotting. * P<0.05 and ** P<0.01. ASIC1a, acid-sensing ion channel 1a; sh, short hairpin; GSC, glioblastoma stem cells; ALDH1, aldehyde dehydrogenase 1.

    Article Snippet: Rabbit polyclonal anti-Notch3 antibody (product code ab60087) was purchased from Abcam.

    Techniques: Transfection, Control, Expressing, Western Blot

    Examples of the expression patterns of Notch3 in cases of prostate cancer (A) No expression; (B) Weak expression; (C) Overexpression (immunohistochemical stain, ×200).

    Journal: International Journal of Clinical and Experimental Pathology

    Article Title: The clinicopathologic significance of Notch3 expression in prostate cancer

    doi:

    Figure Lengend Snippet: Examples of the expression patterns of Notch3 in cases of prostate cancer (A) No expression; (B) Weak expression; (C) Overexpression (immunohistochemical stain, ×200).

    Article Snippet: A rabbit polyclonal anti-Notch3 antibody (1:80, clone sc-515825, Santa Cruz, Biotechnology, CA, USA) was incubated with the sections for 1 h at room temperature.

    Techniques: Expressing, Over Expression, Immunohistochemical staining, Staining

    Correlation between pathological factors and the expression of  Notch3  in prostate cancer

    Journal: International Journal of Clinical and Experimental Pathology

    Article Title: The clinicopathologic significance of Notch3 expression in prostate cancer

    doi:

    Figure Lengend Snippet: Correlation between pathological factors and the expression of Notch3 in prostate cancer

    Article Snippet: A rabbit polyclonal anti-Notch3 antibody (1:80, clone sc-515825, Santa Cruz, Biotechnology, CA, USA) was incubated with the sections for 1 h at room temperature.

    Techniques: Expressing